HHV-8 infection in African children.
Identifieur interne : 000F26 ( Main/Exploration ); précédent : 000F25; suivant : 000F27HHV-8 infection in African children.
Auteurs : Loredana Sarmati [Italie]Source :
- Herpes : the journal of the IHMF [ 0969-7667 ] ; 2004.
Descripteurs français
- KwdFr :
- Afrique subsaharienne (épidémiologie), Femelle, Grossesse, Herpèsvirus humain de type 8, Humains, Infections à Herpesviridae (), Infections à Herpesviridae (sang), Infections à Herpesviridae (épidémiologie), Infections à Herpesviridae (étiologie), Nouveau-né, Services de santé pour enfants, Études séroépidémiologiques.
- MESH :
- sang : Infections à Herpesviridae.
- épidémiologie : Afrique subsaharienne, Infections à Herpesviridae.
- étiologie : Infections à Herpesviridae.
- Femelle, Grossesse, Herpèsvirus humain de type 8, Humains, Infections à Herpesviridae, Nouveau-né, Services de santé pour enfants, Études séroépidémiologiques.
English descriptors
- KwdEn :
- Africa South of the Sahara (epidemiology), Child Health Services, Female, Herpesviridae Infections (blood), Herpesviridae Infections (epidemiology), Herpesviridae Infections (etiology), Herpesviridae Infections (prevention & control), Herpesvirus 8, Human, Humans, Infant, Newborn, Pregnancy, Seroepidemiologic Studies.
- MESH :
- geographic , epidemiology : Africa South of the Sahara.
- blood : Herpesviridae Infections.
- epidemiology : Herpesviridae Infections.
- etiology : Herpesviridae Infections.
- prevention & control : Herpesviridae Infections.
- Child Health Services, Female, Herpesvirus 8, Human, Humans, Infant, Newborn, Pregnancy, Seroepidemiologic Studies.
Abstract
Human herpesvirus 8 (HHV-8) is prevalent in Africa and parts of southern Europe, but less common elsewhere. It is analogous to its distant relative, the Epstein-Barr virus, in that it rarely causes disease in the immunocompetent host but is highly oncogenic when associated with immunosuppression or HIV-1 infection. HHV-8 infection is endemic in sub-Saharan Africa, where high seroprevalence rates of up to 58% in young children were found in Ghana, Tanzania, Cameroon, Uganda and Egypt. Paediatric HHV-8 transmission has been studied in various African populations. Frequent detection of the virus from oral secretions suggests the horizontal route is the most common way to acquire the virus during childhood. A clinical presentation characterized by a self-limited maculopapular rash and fever was associated with HHV-8 primary infection in Egyptian children.
PubMed: 15955270
Affiliations:
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wicri:level="3"><nlm:affiliation>Department of Public Health, Chair of Infectious Diseases, Tor Vergata University, Rome, Italy. sarmati@med.uniroma2.it</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Public Health, Chair of Infectious Diseases, Tor Vergata University, Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation></author></analytic><series><title level="j">Herpes : the journal of the IHMF</title><idno type="ISSN">0969-7667</idno><imprint><date when="2004" type="published">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Africa South of the Sahara (epidemiology)</term><term>Child Health Services</term><term>Female</term><term>Herpesviridae Infections (blood)</term><term>Herpesviridae Infections (epidemiology)</term><term>Herpesviridae Infections 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qualifier="epidemiology" xml:lang="en"><term>Herpesviridae Infections</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Herpesviridae Infections</term></keywords><keywords scheme="MESH" qualifier="prevention & control" xml:lang="en"><term>Herpesviridae Infections</term></keywords><keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Infections à Herpesviridae</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Afrique subsaharienne</term><term>Infections à Herpesviridae</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Infections à Herpesviridae</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Child Health Services</term><term>Female</term><term>Herpesvirus 8, Human</term><term>Humans</term><term>Infant, Newborn</term><term>Pregnancy</term><term>Seroepidemiologic Studies</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Femelle</term><term>Grossesse</term><term>Herpèsvirus humain de type 8</term><term>Humains</term><term>Infections à Herpesviridae</term><term>Nouveau-né</term><term>Services de santé pour enfants</term><term>Études séroépidémiologiques</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Human herpesvirus 8 (HHV-8) is prevalent in Africa and parts of southern Europe, but less common elsewhere. It is analogous to its distant relative, the Epstein-Barr virus, in that it rarely causes disease in the immunocompetent host but is highly oncogenic when associated with immunosuppression or HIV-1 infection. HHV-8 infection is endemic in sub-Saharan Africa, where high seroprevalence rates of up to 58% in young children were found in Ghana, Tanzania, Cameroon, Uganda and Egypt. Paediatric HHV-8 transmission has been studied in various African populations. Frequent detection of the virus from oral secretions suggests the horizontal route is the most common way to acquire the virus during childhood. A clinical presentation characterized by a self-limited maculopapular rash and fever was associated with HHV-8 primary infection in Egyptian children.</div></front></TEI><affiliations><list><country><li>Italie</li></country><region><li>Latium</li></region><settlement><li>Rome</li></settlement></list><tree><country name="Italie"><region name="Latium"><name sortKey="Sarmati, Loredana" sort="Sarmati, Loredana" uniqKey="Sarmati L" first="Loredana" last="Sarmati">Loredana Sarmati</name></region></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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